When you submit your website to search engines, directories, or classifieds, you should never attempt to use an autoresponder address. Most of these website types use autoresponders themselves, when they send out their messages. If their autoresponder happens to send a message out to your autoresponder, they will continue responding – which can be very annoying.
When you decide to subscribe to an email or ezine you should always use your valid email address and never use the address for your autoresponder. If you use your autoresponder to subscribe, chances are you’ll have your subscription revoked. It can be very annoying if a group sends out emails, only to find that your autoresponder keeps sending return messages. For that very reason, you should never use your autoresponder address to subscribe to anything.